Sulfamethoxazole Trimethoprim side effects

Indications for use of Sulfamethoxazole / Trimethoprim:

Urinary infections: urethritis, cystitis, pielit, pyelonephritis, epididimit, gonorrhoea (male and female), soft chancre, venereal lymphogranuloma, groin granulomas;

Respiratory tract infections: bronchitis (acute and chronic), Bronhoektaticheskaya disease, lobar pneumonia, bronchopneumonia, Pneumocystis pneumonia;

Ear infections: Medium, sinusitis, laryngitis, angina; Fever;

Typhoid fever, cholera, dysentery, cholecystitis, cholangitis, gastroenteritis

Infections of skin and soft tissues: acne, furunculosis, pyoderma, Ranev infections;

Osteomyelitis (acute and chronic), etc. Osteoartikuljarnye infections, brucellosis (acute), South Blastomycosis, malaria (Plasmodium falciparum), toxoplasmosis (Integrated therapy).

 

Contraindications:

Hypersensitivity to the components of sulfamethoxazole/trimethoprim (including sulfanilamidam), liver and/or renal failure (cc less than 15 ml/min), Aplastichesk anaemia, B12-deficiency anaemia, agranulocytosis, lejkopeni, lack of glucose-6-fosfatdegidrogenaza, pregnancy, lactation period period, Pneumocystis pneumonia and age 6 (for I/O), child age (up to 3 months for oral admission), hyperbilirubinemia for children.

With caution. Folic acid deficiency, bronchial asthma, thyroid disease.

Side effects:

On the part of the nervous system: headache, dizziness; In some cases, aseptically meningitis, depression, apathy, tremor, peripheral neuritis.

On the side of the respiratory system: bronchospasm, pulmonary infiltrates.

From the digestive system: nausea, vomiting, reduced appetite, diarrhoea, gastritis, abdominal pain, glossitis, mouth, cholestasis, increased activity of “liver” Transaminaz, hepatitis, Gepatonekros, pseudomembranous enterocolitis.

By the Krovetvoreni authorities: Lejkopeni, neutropenia, thrombocytopenia, agranulocytosis, megaloblastic anaemia.

From the urinary system: Polyuria, interstitial jade, kidney dysfunction, Christalluria, increased concentration of urea, Hypercreatinemia, toxic nephropathy with this medicine and Anuria.

On the side of the musculoskeletal system: arthralgia, myalgia.

Allergic reactions: itching, animals, rash, multiform exudative erythema (including Stevens-Johnson syndrome), Toxic epidermal Nekroliz (Lyell syndrome), exfoliative dermatitis, allergic myocarditis, elevated body temperature, angioedema edema, Giperem skler.

Local reactions: Thrombophlebitis (in the place of venipuncture), pain at the place of introduction.

Other: hypoglycemia.

Overdose sulfamethoxazole/Trimethoprim. Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, unconscious state, confusion, visual impairment, fever, any, christalluria; With a prolonged overdose-thrombocytopenia, Lejkopeni, megaloblastic anaemia, jaundice.

Treatment: Pumping of the stomach, acidification of urine increases have, ingestion of fluid, in/M-5-15 mg/folinata of calcium (eliminates the have on bone marrow), if necessary dialysis.

 

Frequently used in all types of prostatitis. Sulfamethoxazole trimethoprim in prostate infections, sulfamethoxazole trimethoprim in prostatitis, sulfamethoxazole trimethoprim in acute prostatitis, sulfamethoxazole trimethoprim in chronic prostatitis, sulfamethoxazole trimethoprim in bacterial prostatitis, sulfamethoxazole trimethoprim in abacterial prostatitis